Thermo Fisher Scientific PSMD11 Polyclonal Antibody
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Thermo Fisher Scientific의 PSMD11 Polyclonal Antibody는 인간 및 마우스 반응성을 가진 Rabbit IgG 항체로, Western blot과 Immunoprecipitation에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공되어 안정적인 단백질 분석에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 372 and 422 of Human Proteasome (Prosome, Macropain) 26S Subunit, non-ATPase, 11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Rat, Zebrafish, X. tropicalis, and Bovine
Target Information
The 26S proteasome (PSMD11) is a multicatalytic proteinase complex composed of a 20S core and a 19S regulator.
- The 20S core consists of four rings of 28 non-identical subunits (two rings of 7 alpha and two rings of 7 beta subunits).
- The 19S regulator includes a base (6 ATPase and 2 non-ATPase subunits) and a lid (up to 10 non-ATPase subunits).
Proteasomes are abundant in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal pathway.
The immunoproteasome plays an essential role in processing class I MHC peptides.
PSMD11 is a non-ATPase subunit of the 19S regulator.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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