Thermo Fisher Scientific GPX3 Polyclonal Antibody
Thermo Fisher Scientific의 GPX3 Polyclonal Antibody는 인간 및 랫트 시료에 반응하는 토끼 유래 IgG 항체로, 동결 조직 면역조직화학(IHC-F)에 적합합니다. 합성 펩타이드 면역원 기반으로 제작되었으며, 라이오필라이즈드 형태로 보존성이 우수합니다. 연구용으로만 사용됩니다.
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Applications
- Immunohistochemistry (Frozen) (IHC-F)
Tested Dilution: 1:1,000–1:5,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues F(135)-N(154) of human glutathione peroxidase 3 (GPx-P), conjugated to diphtheria toxin |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2112273 |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
After reconstitution, store aliquots at -20°C for higher stability, or at 4°C with an appropriate antibacterial agent.
Avoid repetitive freeze/thaw cycles.
Target Information
Glutathione peroxidases (Gpxs) are ubiquitously expressed enzymes that catalyze the reduction of hydrogen and organic hydroperoxides using glutathione.
There are several isoforms differing in structure and localization:
- GPx1 (cGPx): Cytosolic/mitochondrial, selenium-dependent.
- GPx2 (GI-GPx): Expressed in gastrointestinal epithelium.
- GPx3 (pGPx): Extracellular plasma form, mainly expressed in kidney and released into blood.
- GPx4 (PH-GPx): Reduces hydroperoxides in membranes and lipids.
- GPx5 (eGPx): Epididymis-specific secretory form.
All mammalian GPx family members, except Cys-containing GPx3 and GPx5, possess selenocysteine at the active site.
For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.
제품 이미지
(PA1-18280_GPX3_P22352-1_Rabbit.svg)
(PA1-18280_GPX3_P22352-1_Rabbit_PDP.jpeg)
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