Thermo Fisher Scientific PTPRE Monoclonal Antibody (OTI3B8), TrueMAB
PTPRE 단백질을 인식하는 Mouse IgG1 단클론 항체로, WB, ICC/IF, Flow Cytometry에 사용 가능. HEK293T 세포에서 발현된 human recombinant protein을 면역원으로 제작. 0.5 mg/mL 농도의 액상 형태로, PBS/BSA/glycerol buffer에 보존. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3B8 |
| Immunogen | Full length human recombinant protein of human PTPRE produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate various cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation.
Two alternatively spliced transcript variants of this gene have been reported:
- A receptor-type PTP with a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains.
- A nonreceptor-type isoform with a distinct hydrophilic N-terminus.
Studies in mice suggest regulatory roles of this PTP in RAS-related signal transduction pathways, cytokine-induced STAT signaling, and activation of voltage-gated K⁺ channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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