Thermo Fisher Scientific PTPRE Monoclonal Antibody (OTI4B2), TrueMAB
PTPRE 단백질을 인식하는 Mouse Monoclonal Antibody로 Western Blot, IHC, ICC, Flow Cytometry에 사용 가능. Human 시료 반응성. Affinity chromatography로 정제된 액상 항체로, 안정적인 PBS/BSA/glycerol buffer에 보관. 연구용 전용 제품.
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- TA501028
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4B2 |
| Immunogen | Full length human recombinant protein of human PTPRE produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.89 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate various cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported:
- One encodes a receptor-type PTP with a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains.
- The other encodes a nonreceptor-type isoform with a distinct hydrophilic N-terminus.
Studies in mice suggest regulatory roles of this PTP in RAS-related signal transduction, cytokine-induced STAT signaling, and activation of voltage-gated K⁺ channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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