
Thermo Fisher Scientific PTPRE Monoclonal Antibody (OTI5E8), TrueMAB
PTPRE 단백질을 인식하는 마우스 단클론 항체로, Western blot, IHC, ICC 등 다양한 응용에 적합. Human 시료 반응성, 비결합형 액상 포맷, 고순도 친화 크로마토그래피 정제. 세포 성장 및 신호전달 연구에 유용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5E8 |
| Immunogen | Full length human recombinant protein of human PTPRE produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate various cellular processes such as cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants have been reported:
- A receptor-type PTP with a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains.
- A nonreceptor-type isoform containing a distinct hydrophilic N-terminus.
Studies in mice suggest that this PTP regulates RAS-related signal transduction pathways, cytokine-induced STAT signaling, and activation of voltage-gated K⁺ channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
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