Thermo Fisher Scientific PGRMC2 Polyclonal Antibody
PGRMC2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunocytochemistry에 적합하며, Human, Mouse, Rat 반응성. 고순도 항원 친화 크로마토그래피 정제 제품으로 안정적 액상 형태 제공.
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- PA575547
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the 178–223 of Human PGRMC2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719275 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
PGRMC2 (progesterone receptor membrane component 2), also known as DG6 or PMBP, is a single-pass membrane protein belonging to the cytochrome b5 family (MAPR subfamily). It is expressed in sperm and believed to function as a steroid receptor involved in the progesterone-dependent sperm acrosome reaction. PGRMC2 shares approximately 50% sequence identity with PGRMC1. Loss of PGRMC2 gene is associated with metastasis in uterine endocervical adenocarcinomas, suggesting a role in metastasis suppression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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