Thermo Fisher Scientific SP1 Polyclonal Antibody
SP1 단백질을 인식하는 염소 유래 폴리클로날 항체로, Western blot에 적합합니다. 마우스 시료에 반응하며, 0.3–1 µg/mL 농도로 사용 권장됩니다. 액상 형태로 제공되며, TBS(pH 7.3)와 0.5% BSA, 0.02% sodium azide를 포함합니다. -20°C에서 보관하십시오.
- 카탈로그번호
- PA5142435
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 0.3–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-DGIHDETAGGEGEN |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933083 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:8,000.
Target Information
SP1 is a transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. It binds with high affinity to GC-rich motifs and regulates expression of numerous genes involved in processes such as cell growth, apoptosis, differentiation, and immune responses. SP1 activity is highly regulated by post-translational modifications including phosphorylation, sumoylation, proteolytic cleavage, glycosylation, and acetylation. It also binds the PDGFR-alpha G-box promoter and may modulate cellular responses to DNA damage. SP1 is implicated in chromatin remodeling and plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter, as well as in the regulation of FE65 gene expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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