Thermo Fisher Scientific ITIH4 Polyclonal Antibody
Human ITIH4 단백질을 인식하는 Goat Polyclonal Antibody로, WB 및 IHC(P)에서 검증됨. 0.5 mg/mL 농도의 액상 형태이며, TBS(pH 7.3) 버퍼에 0.5% BSA 포함. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.03 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 4–6 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence ERLCVDPRHRQGPVN |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933085 |
Product Specific Information
- The immunizing peptide represents a region of the 35 kDa chain, which is glycosylated, resulting in an apparent higher molecular weight.
- This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
The inter-alpha-trypsin inhibitor (ITI, I-alpha-I) family is a classic example of protein-glycosaminoglycoprotein (PGP) complexes.
They occur constitutively in plasma at relatively high concentrations and result from alternating combinations of three kinds of heavy chains with a common light chain called the bikunin proteoglycan.
Bikunin has two proteinase inhibitor domains and belongs to the Kunitz-type protease inhibitor family; it displays inhibitory activity against trypsin, leukocyte elastase, and plasmin.
The heavy chains do not have protease inhibitory properties but can interact with hyaluronic acid, promoting the stability of the extracellular matrix.
The ITI protein family is suspected of playing a key role in extracellular matrix biology.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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