Thermo Fisher Scientific Interleukin-3 (IL-3) Monoclonal Antibody (IL3/4001)
인간 IL-3를 특이적으로 인식하는 마우스 단클론 항체로, 다양한 면역조직화학 및 펩타이드 배열 분석에 사용 가능. 고순도 Protein A/G 정제, 액상 형태로 제공되며 4°C에서 안정적 보관. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | IL3/4001 |
| Immunogen | Recombinant fragment of human IL3 protein (exact sequence is proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Interleukin 3 (IL-3), also known as Mast Cell Growth Factor (MCGF), Multi-Colony Stimulating Factor (multi-CSF), or Eosinophil-CSF (E-CSF), is produced by activated T cells, mast cells, and eosinophils.
IL-3 is a hematopoietic growth factor that stimulates colony formation of erythroid, megakaryocyte, neutrophil, eosinophil, basophil, mast cell, and monocytic lineages.
Most functions are enhanced or dependent on co-stimulation with other cytokines. Human and mouse IL-3 share only 29% sequence identity at the amino acid level, and bioactivity is highly species-specific — human IL-3 has no activity on mouse cells.
IL-3 supports proliferation and differentiation of various hematopoietic cells and is involved in cell growth, differentiation, apoptosis, and may possess neurotrophic activity associated with neurologic disorders.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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