Thermo Fisher Scientific Interleukin-3 (IL-3) Monoclonal Antibody (IL3/4003)
인간 IL-3에 특이적인 마우스 모노클로날 항체로, 면역조직화학(IHC) 및 펩타이드 어레이에 사용 가능. 단백질 A/G로 정제된 액상 형태이며, 보존제 무첨가 PBS 버퍼에 저장. 인간 흉선 또는 편도 조직을 양성 대조로 사용 가능.
- 카탈로그번호
- 3562-MSM3-P1ABX
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | IL3/4003 |
| Immunogen | Recombinant fragment of human IL3 protein (exact sequence is proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive Control: Human thymus or tonsil tissue
- Cellular Location: Secreted
Target Information
Interleukin 3 (IL-3), also known as Mast Cell Growth Factor (MCGF), Multi-Colony Stimulating Factor (multi-CSF), or Eosinophil-CSF (E-CSF), is produced by activated T cells, mast cells, and eosinophils.
IL-3 is a hematopoietic growth factor that stimulates colony formation of erythroid, megakaryocyte, neutrophil, eosinophil, basophil, mast cell, and monocytic lineages.
Its functions are enhanced or dependent on co-stimulation with other cytokines.
Human and mouse IL-3 share only 29% sequence identity at the amino acid level, and the bioactivity of IL-3 is highly species-specific — human IL-3 has no activity on mouse cells.
IL-3 supports proliferation of various hematopoietic cell types and is involved in cell growth, differentiation, and apoptosis.
It also possesses neurotrophic activity and may be associated with neurologic disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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