
Thermo Fisher Scientific CD26 Monoclonal Antibody (5E8)
Rat CD26 단백질을 검출하는 Mouse IgG1 단클론 항체로, WB, IHC(F), ELISA, IP 등 다양한 응용에 적합. Protein G로 정제된 액상형 항체이며 PBS/BSA buffer에 보존. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:50 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:50 |
| ELISA | 1:50 |
| Immunoprecipitation (IP) | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5E8 |
| Immunogen | Crude rat liver membrane extracts |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1071821 |
Product Specific Information
- MA1-40245 detects CD26 from rat samples.
- Successfully used in ELISA, immunohistochemistry (frozen), immunoprecipitation, and Western blot applications.
- Immunogen is rat CD26.
Target Information
CD26 (dipeptidyl peptidase IV, DPP IV; adenosine deaminase binding protein) is a homodimeric atypical serine protease belonging to the prolyl oligopeptidase family.
It is expressed on lymphocytes and upregulated during T-cell activation, also found on activated B cells, NK cells, and epithelial tissues.
CD26 plays roles in T-cell activation, cell adhesion to extracellular matrix proteins such as fibronectin and collagen, and HIV infection.
Altered CD26 peptidase activity is linked to malignant transformation, with increased enzymatic activity correlating to tumor grade and severity.
Expression changes have been observed in monocytes and CD4+ T cells during rheumatoid arthritis and systemic lupus erythematosus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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