Thermo Fisher Scientific ADAMTS5 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:100-1:1,000

-

Immunocytochemistry (ICC/IF)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to residues C I(442) L T S I D A S K P(451) of human ADAMTS5. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ADAMTS5,uniProtId:Q9UNA0-1,ncbiNodeId:9606,antigenRange:442-451,antigenLength:930,antigenImageFileName:PA1-1742_ADAMTS5_Q9UNA0-1_Rabbit.svg,antigenImageFileNamePDP:PA1-1742_ADAMTS5_Q9UNA0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with 1mg/mL BSA

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_557478

Product Specific Information

PA1-1742 detects ADAMTS5 in human samples.

PA1-1742 has been successfully used in Western blot procedures. In Western blot analysis of JJ012 cells this antibody detects a ~64 kDa protein representing ADAMTS5.

The PA1-1742 immunogen is a synthetic peptide corresponding to residues C I(442) L T S I D A S K P(451) of human ADAMTS5.

Target Information

ADAMTS5, also known as Implantin or Aggrecanase 2, is a member of the larger family of ADAMs (A Disintegrin And Metalloproteinase) metalloproteinases containing thrombospondin (TS) repeats. ADAMTS5 (A Disintegrin And Metalloproteinase with Thrombospondin-5 motif) was first described as ADAMTS5, a protein elevated in mice during the peri-implantion period. At the same time, another group identified Aggrecanase 11, a protein elevated in arthritic synovium. The name was later changed to ADAMTS5. ADAMTS5 is expressed in human and mouse. It has been found in heart, lung, cervix, uterus, ovary, brain, cartilage, and numerous other tissues, as well as chondroblastoma cell lines.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.