Thermo Fisher Scientific MIA Polyclonal Antibody
Thermo Fisher Scientific의 MIA Polyclonal Antibody는 인간, 마우스, 랫트 시료에서 MIA 단백질 검출에 적합한 고순도 항체입니다. Western blot에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제되었습니다. 비결합형 액상 형태로 1 mg/mL 농도이며 연구용으로만 사용됩니다.
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Thermo Fisher Scientific MIA Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:1,000
Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in Human MIA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2719615 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% as confirmed by SDS-PAGE.
Target Information
Tumorigenesis is mediated by a network of membrane, cytosolic, and nuclear factors regulating proliferation and cell-matrix interactions through signaling cascades. Melanoma inhibitory activity (MIA, also known as CD-RAP) is a SH3-like domain-containing protein secreted from chondrocytes and malignant melanoma cells.
MIA is translated as a 131-amino acid pro-form and processed into a mature 107-amino acid protein after cleavage of its secretion signal. It is expressed during chondrogenesis and in mature chondrocytes, necessary for maintaining normal cartilage cell phenotype.
MIA mRNA is found in carcinomas of the colon, ovary, kidney, and head/neck, and may serve as a marker for monitoring melanomic activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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