Thermo Fisher Scientific Ly-6E Polyclonal Antibody

Thermo Fisher Scientific Ly-6E Polyclonal Antibody

Applications

• Western Blot (WB)

Tested Dilution: 1:500–1:1,000

Species Reactivity

• Human
• Mouse
• Rat

Product Specifications

Product Specific Information

The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).

Target Information

Sca1, also known as Ly6A/E, is a member of the Ly6 multigene family of type V GPI-anchored cell surface proteins. It is expressed on multipotent hematopoietic stem cells in mouse bone marrow with both Ly6.1 and Ly6.2 allotypes.
In peripheral tissues, Sca1 expression varies between allotypes:

• Ly6.1 strains (A, BALB/c, CBA, C3H/He, DBA/1, NZB): Few Sca1⁺ resting peripheral lymphocytes
• Ly6.2 strains (AKR, C57BL, C57BR, C57L, DBA/2, PL, SJL, SWR, 129): High numbers of Sca1⁺ lymphocytes
  Sca1 expression is dramatically upregulated in all strains upon cellular activation.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.