Thermo Fisher Scientific TADA3L Polyclonal Antibody
Human TADA3L 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western Blot에 적합. Protein A로 정제된 고농도 액상 시약. p53 관련 전사 활성 연구에 활용 가능. 4°C 단기, -20°C 장기 보관 권장.
- 판매단위
- pk
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Applications
- Western Blot (WB): Tested dilution 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 251–432 of Human TADA3L |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 9.46 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545067 |
Product Specific Information
- Recommended positive control: TADA3L-transfected 293T cells
- Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (90%), Pig (100%), Rhesus Monkey (100%), Chimpanzee (99%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Many DNA-binding transcriptional activator proteins enhance RNA polymerase II-mediated gene transcription by interacting with the general transcription machinery at the basal promoter. Adaptor proteins such as TADA3L may acetylate and destabilize nucleosomes, relieving chromatin constraints at the promoter. TADA3L is part of the PCAF histone acetylase complex and associates with tumor suppressor protein p53, being required for full p53 activity and apoptosis. Multiple alternatively spliced variants exist, though some full-length forms remain undetermined.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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