Thermo Fisher Scientific TPH2 Polyclonal Antibody
TPH2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간, 생쥐, 랫트 등 다양한 종에 반응하며 WB, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제된 고품질 항체로, 신경전달물질 연구에 적합.
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Thermo Fisher Scientific TPH2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 178–490 of Human TPH2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545060 |
Product Specific Information
- Recommended positive controls: HeLa, U87-MG, SK-N-SH, IMR-32, SK-N-AS, Raw264.7, C2C12, mouse hippocampus, mouse midbrain
- Predicted reactivity: Mouse (97%), Rat (99%), Zebrafish (91%), Japanese Medaka (90%), Dog (95%), Chicken (97%), Rhesus Monkey (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Tryptophan hydroxylase (TPH) is a member of the pterin-dependent aromatic acid hydroxylase family. It catalyzes the first and rate-limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. TPH is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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