Thermo Fisher Scientific SR-BI Polyclonal Antibody
SR-BI 단백질 검출용 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunohistochemistry에 최적화. 인간, 마우스, 랫트 반응성. 고순도 항원 친화 크로마토그래피 정제. 연구용으로만 사용.
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Thermo Fisher Scientific SR-BI Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (IHC) | 2.5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 15 amino acid peptide near the amino terminus of human SCARB1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152099 |
Product Specific Information
- A suggested positive control is human spleen tissue lysate.
- PA5-20756 can be used with blocking peptide PEP-0870.
Target Information
High density lipoproteins (HDLs) play a critical role in cholesterol metabolism, and their plasma concentrations are inversely correlated with the risk for atherosclerosis.
SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester.
It is expressed primarily in liver and nonplacental steroidogenic tissues and mediates selective cholesterol uptake by a distinct mechanism.
In mice, SR-BI plays a key role in determining plasma lipoprotein cholesterol levels and cholesterol accumulation in the adrenal gland.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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