Thermo Fisher Scientific HGF Monoclonal Antibody (9B6)
HGF 단백질을 인식하는 Mouse monoclonal antibody로 Western blot에 적합. Human 시료 반응성. Protein G로 정제된 액상 형태이며, -20°C에서 보관. 세포 성장과 이동을 조절하는 HGF 연구용에 적합.
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Applications
- Western Blot (WB): 1:1,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 9B6 |
| Immunogen | This HGF antibody is generated from mice immunized with a KLH-conjugated synthetic peptide between amino acids 521–554 of human HGF. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein G |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Hepatocyte growth factor (HGF) regulates cell growth, motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the c-Met receptor. It is secreted by mesenchymal cells and acts as a multifunctional cytokine on epithelial cells. HGF stimulates mitogenesis, cell motility, and matrix invasion, playing a central role in angiogenesis, tumorigenesis, and tissue regeneration. It is secreted as a single inactive polypeptide that is cleaved into a 69-kDa alpha chain and a 34-kDa beta chain, forming an active heterodimer through a disulfide bond. The protein belongs to the plasminogen subfamily of S1 peptidases but lacks protease activity. Alternative splicing produces multiple isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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