Thermo Fisher Scientific CYP1A1 Monoclonal Antibody (10G3)
인간 CYP1A1 단백질을 인식하는 마우스 단클론 항체로, Western Blot에 적합합니다. 단백질 대사 관련 연구에 활용되며, Protein G로 정제된 액상 형태입니다. -20°C에서 보관하며, 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 10G3 |
| Immunogen | This CYP1A1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 377–405 amino acids from the C-terminal region of human CYP1A1. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein G |
| Storage buffer | TBS, pH 7.4, with 1% BSA, 40% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The CYP1A1 gene encodes a member of the cytochrome P450 superfamily of enzymes. These proteins are monooxygenases that catalyze reactions involved in drug metabolism and the synthesis of cholesterol, steroids, and other lipids.
CYP1A1 localizes to the endoplasmic reticulum, and its expression is induced by certain polycyclic aromatic hydrocarbons (PAHs), including compounds found in cigarette smoke.
Although its endogenous substrate is unknown, CYP1A1 can metabolize some PAHs into carcinogenic intermediates. The gene is associated with lung cancer risk.
A related family member, CYP1A2, is located approximately 25 kb away on chromosome 15.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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