Thermo Fisher Scientific BCL2L1 Monoclonal Antibody (4C4)
BCL2L1 단백질을 인식하는 단클론 항체로, Western blot에 적합합니다. Human, Mouse, Rat 시료에 반응하며, IgG1 아이소타입입니다. 단백질 G로 정제되었으며, TBS buffer에 보존됩니다. 세포 사멸 관련 연구용으로 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4C4 |
| Immunogen | Purified His-tagged BCL2L1 protein was used to produce this monoclonal antibody. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein G |
| Storage Buffer | TBS, pH 7.4, with 1% BSA, 40% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by the BCL-X gene belongs to the BCL-2 protein family. Members of this family form hetero- or homodimers and act as anti- or pro-apoptotic regulators involved in various cellular activities. These proteins are located at the outer mitochondrial membrane and regulate the opening of the mitochondrial channel (VDAC).
VDAC controls mitochondrial membrane potential, reactive oxygen species production, and cytochrome C release—key factors in apoptosis induction.
Alternative splicing results in multiple transcript variants encoding two isoforms: the longer isoform acts as an apoptotic inhibitor, while the shorter isoform acts as an apoptotic activator.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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