Thermo Fisher Scientific SRC3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

2 µg/mL

View 11 publications 11 publications

Product Specifications

Species Reactivity

Human

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to residues G(3) L G E N L D P L A S D S(15) C of human AIB1. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SRC3,uniProtId:Q9Y6Q9-1,ncbiNodeId:9606,antigenRange:3-15,antigenLength:1424,antigenImageFileName:PA1-845_SRC3_Q9Y6Q9-1_Rabbit.svg,antigenImageFileNamePDP:PA1-845_SRC3_Q9Y6Q9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with 1mg/mL BSA

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2151061

Product Specific Information

PA1-845 detects amplified in breast cancer 1 (AIB1) from human tissues and cells.

PA1-845 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~155 kDa protein representing AIB1 from T47D cell lysate.

The PA1-845 immunogen is a synthetic peptide corresponding to residues G(3) L G E N L D P L A S D S(15) C of human AIB1.

PA1-845 can be used with blocking peptide PEP-049.

Target Information

AIB1-AC3 recognizes AIB1, a member of the SRC-1 family of nuclear receptor coactivators with an apparent molecular weight of 160kDa. The AIB1 gene has been mapped to region 20q12 and has been shown to be amplified in breast tumors and pancreatic cancer cell lines. AIB1 interacts in a ligand-dependent fashion with the estrogen receptor to enhance estrogen-dependent transcriptional gene activation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.