Thermo Fisher Scientific SPA17 Monoclonal Antibody (OTI1D9), TrueMAB

Applications

• Western Blot (WB)
  Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional round of desalting (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The SPA17 gene encodes a protein located on the cell surface.

• The N-terminus shows similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa).
• The C-terminus contains an IQ calmodulin-binding motif.
• The central region includes carbohydrate-binding motifs, suggesting a role in cell-cell adhesion.
  Originally identified in sperm binding to the zona pellucida, SPA17 is now known to participate in broader cell adhesion functions such as immune cell migration and metastasis.
  A retrotransposed pseudogene is found on chromosome 10q22.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.

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