Thermo Fisher Scientific SPA17 Monoclonal Antibody (OTI1H6), TrueMAB

Applications

Tested Application

• Western Blot (WB)

Recommended Dilution

• 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

This gene encodes a cell surface protein.

• The N-terminus shows similarity to the human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa).
• The C-terminus contains an IQ calmodulin-binding motif.
• The central region includes carbohydrate-binding motifs, likely functioning in cell-cell adhesion.
• Initially identified for its role in sperm binding to the zona pellucida of the oocyte.
• Recent studies suggest additional roles in immune cell migration and metastasis.
• A retrotransposed pseudogene is located on chromosome 10q22.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.