Thermo Fisher Scientific TRPV2 Polyclonal Antibody
TRPV2 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 5–10 µg/mL 농도로 사용 가능. 인간 시료 반응성이 확인되었으며, 항원 친화 크로마토그래피로 정제됨. 4°C 단기 보관, -20°C 장기 보관 권장.
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- PA534289
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 5–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 15 amino acid peptide from internal region of human TRPV2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551641 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla, Gibbon (100%); Monkey (93%); Marmoset (87%).
Target Information
VLR-1 (also known as TRPV2) is a calcium-permeable, non-selective cation channel with outward rectification. It is regulated partly by growth factors such as IGF1, PDGF, and morphogenetic neuropeptide/head activator. Unlike TRPV1, VRL-1 does not respond to capsaicin, acid, or moderate heat but is activated by high temperatures (~52°C). Within sensory ganglia, VRL-1 is expressed mainly in medium- to large-diameter neurons, suggesting a role in high-threshold heat response. VRL-1 transcripts are also found outside the sensory nervous system, indicating activation by other stimuli. VRL-1 is one of six members of the vanilloid-like TRP-channel family, now known as the TRPV family.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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