Thermo Fisher Scientific Phospho-MEK7 (Thr275) Polyclonal Antibody
Phospho-MEK7 (Thr275) 폴리클로날 항체로, 인간·마우스·랫트 시료의 인산화된 MKK7 검출에 적합. Western blot과 IHC(P) 응용 가능. 1 mg/mL 액상 형태로 PBS/글리세롤 완충액에 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MKK7 around the phosphorylation site of Thr275 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899241 |
Product Specific Information
This antibody detects endogenous levels of MKK7 only when phosphorylated at Thr275.
Target Information
The protein encoded by this gene is a dual specificity protein kinase belonging to the MAP kinase family. It specifically activates MAPK8/JNK1 and MAPK9/JNK2 and is itself phosphorylated and activated by MAP kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2, MAP3K3/MEKK5, and MAP4K2/GCK. This kinase mediates cell responses to proinflammatory cytokines and environmental stresses. Multiple alternatively spliced transcript variants exist, with one major supported variant.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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