Thermo Fisher Scientific Clusterin/Apolipoprotein J (APO-J) Monoclonal Antibody (CLU/4724)
Clusterin/Apolipoprotein J 단백질을 인식하는 마우스 단클론 항체로, IHC(P), IHC(PFA), Peptide Array에 적용 가능. Human 시료 반응성. Protein A/G 정제, 1 mg/mL 농도, PBS(pH 7.4) 용액 형태. -20°C 보관, 동결/해동 반복 피할 것.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | - |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL | - |
| Peptide Array (Array) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CLU/4724 |
| Immunogen | Recombinant fragment (around aa150–300) of human CLU protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Isoform 1 functions as an extracellular chaperone that prevents aggregation of nonnative proteins and stress-induced aggregation of blood plasma proteins. It inhibits amyloid fibril formation by several aggregation-prone proteins and maintains partially unfolded proteins for refolding by other chaperones. Secreted isoform 1 protects cells from apoptosis and complement-mediated cytolysis. Intracellular isoforms promote ubiquitination and proteasomal degradation of target proteins, modulate NF-kappa-B activity, and regulate apoptosis and cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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