Thermo Fisher Scientific MYO18A Polyclonal Antibody
Human, Mouse, Rat에 반응하는 Rabbit Polyclonal MYO18A 항체. Western blot에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제됨. Golgi 막 및 세포골격 관련 연구에 적합. PBS/glycerol buffer에 보관, 장기 저장 시 -20°C 권장.
- 카탈로그번호
- PA576549
- 판매단위
- pk
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Thermo Fisher Scientific MYO18A Polyclonal Antibody
Applications
- Western Blot (WB): 1:1,000–1:2,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein of human MYO18A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720276 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% as confirmed by SDS-PAGE.
Target Information
MYO18A may link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. It may play a role in Golgi membrane trafficking and contribute to maintaining the flattened shape of the Golgi apparatus.
Additionally, in cooperation with LURAP1 and CDC42BPA/CDC42BPB, MYO18A is involved in modulating lamellar actomyosin retrograde flow, which is crucial for cell protrusion and migration.
It may also help maintain stromal cell architectures necessary for cell-to-cell contact, regulate trafficking, expression, and activation of innate immune receptors on macrophages, and suppress inflammatory responsiveness of macrophages by modulating CD14 trafficking.
Usage Note
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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