Thermo Fisher Scientific PTGES2 Polyclonal Antibody
Rabbit polyclonal antibody targeting Human PTGES2, validated for WB, IHC, ICC/IF, and ELISA. Affinity-purified with >95% purity. Suitable for studying prostaglandin E2 biosynthesis and COX pathway interactions. Supplied as liquid, unconjugated, 1 mg/mL...
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:5,000–1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full-length Human PTGES2 (UniProt ID: Q9H7Z7-1, antigen range: 1–377) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720877 |
Product Specific Information
This antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. Purity is greater than 95% as determined by SDS-PAGE.
Target Information
The PTGES2 gene encodes prostaglandin E synthase 2 (PTGES2), an enzyme essential for the biosynthesis of prostaglandin E2 (PGE2) from arachidonic acid. It functions downstream of the cyclooxygenase (COX) pathway, interacting with COX-1 and COX-2. PTGES2 plays key roles in inflammation, fever, and pain responses. As a membrane-associated protein, PTGES2 uniquely regulates PGE2 production and influences immune and vascular signaling processes.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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