Thermo Fisher Scientific KLHL12 Monoclonal Antibody (2G2)
Human KLHL12 단백질을 타겟으로 하는 마우스 단클론 항체로, Western blot 및 ELISA에 적합합니다. 비결합형 액상 포맷이며, 단기 4°C 보관 및 장기 -20°C 보관 권장. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| ELISA | 1:10,000 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2G2 |
| Immunogen | Purified recombinant fragment of human KLHL12 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11004907 |
Product Specific Information
MA5-15649 targets KLHL12 in indirect ELISA and Western Blot applications, showing reactivity with human samples.
The immunogen is a purified recombinant fragment of human KLHL12 expressed in E. coli.
MA5-15649 detects KLHL12 with a predicted molecular weight of approximately 63 kDa.
Target Information
KLHL12 serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex.
It negatively regulates the Wnt signaling pathway via targeted ubiquitination and subsequent proteolysis of DVL3.
Tissue specificity: Highly expressed in testis and at lower levels in the submandibular salivary gland.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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