Thermo Fisher Scientific RET Polyclonal Antibody
RET 단백질의 C-말단 영역을 인식하는 Rabbit Polyclonal 항체. Western blot에 적합하며 인간에 반응. 예측된 교차 반응성: Mouse, Rat, Zebrafish, Dog. 항원 친화 크로마토그래피로 정제된 액상 항체로, 연구용으로만 사용 가능.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the C-terminus region of human RET |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2792266 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (94%), Rat (93%), Zebrafish (80%), Dog (92%).
- Positive Control: U87-MG, SK-N-SH, IMR32, SK-N-AS.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The receptor tyrosine kinase RET is a member of the cadherin superfamily. RET plays a crucial role in neural crest development and can undergo oncogenic activation by cytogenetic rearrangement. RET transduces signals for cell growth and differentiation.
Mutations in the RET gene are associated with multiple endocrine neoplasia type IIA and IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for the RET gene. Additional variants have been described but their biological validity has not been confirmed.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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