Thermo Fisher Scientific SCD Monoclonal Antibody (CD.E10)
SCD 단백질을 인식하는 Mouse monoclonal antibody (Clone CD.E10). Western blot, IHC, ELISA, IP 등 다양한 응용에 사용 가능. 1 mg/mL 농도의 액상 형태로 제공되며, 4°C 단기 보관 및 -20°C 장기 보관 권장. 연구용으로만 사용.
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Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:1,000 | |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | |
| ELISA | Assay-dependent | |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CD.E10 |
| Immunogen | Recombinant, full length human protein (SCD, UniProt ID: O00767-1, amino acids 1–359) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2183106 |
Product Specific Information
- Recommended positive control: 293 cells
- Predicted molecular weight: 41.5 kDa
Target Information
Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an iron-containing enzyme that catalyzes a rate-limiting step in the synthesis of unsaturated fatty acids.
The principal product of SCD is oleic acid, formed by desaturation of stearic acid.
The stearic acid to oleic acid ratio influences cell growth and differentiation via effects on membrane fluidity and signal transduction.
Four SCD isoforms (Scd1–Scd4) exist in mouse, while humans have two (SCD1 and SCD5).
SCD1 shares ~85% amino acid identity with mouse and rat isoforms; SCD5 is unique to primates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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