Thermo Fisher Scientific Calcineurin A Polyclonal Antibody
Calcineurin A 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB, ICC/IF, ChIP 등 다양한 연구용 분석에 적합합니다. 높은 특이성과 재현성을 제공하며, 항원 친화 크로마토그래피로 정제된 액상 형태 제품입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:10,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
| ChIP assay (ChIP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Amphibian, Human, Mouse, Rodent, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 1–264 of Human Calcineurin A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.98 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C and avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2546685 |
Product Specific Information
- Recommended positive controls: Neuro 2A, C8D30, NIH-3T3, Raw264.7, C2C12, Molt-4, U87-MG, SK-N-SH, SK-N-AS, IMR32, JC, BCL-1, rat brain, human Calcineurin A-transfected 293T.
- Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (90%), Xenopus laevis (98%), Dog (100%), Pig (99%), Rabbit (100%), Rhesus Monkey (100%), Bovine (99%).
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. It is found in the nucleus and contains a leucine zipper domain and several PEST motifs, which confer targeted degradation. Alternative splicing results in multiple transcript variants encoding two different isoforms.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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