Thermo Fisher Scientific Calpain 6 Polyclonal Antibody
Calpain 6 단백질을 인식하는 Rabbit Polyclonal 항체로, Human 및 Mouse 시료에 반응합니다. Western blot, IHC(P), ICC/IF에 사용 가능하며, 고순도의 Affinity chromatography로 정제되었습니다. PBS 버퍼(50% glycerol) 내 액상 형태로 제공됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CAPN6 (Accession Q9Y6Q1), corresponding to amino acid residues P346–H396 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853026 |
Product Specific Information
Antibody detects endogenous levels of total CAPN6.
Target Information
Calpain-6, also known as calpamodulin or calpain-X, is an intracellular, calcium-dependent cysteine protease. It shows tissue-specific expression, primarily in the placenta, and during embryonic development in several tissues. Unlike classical calpains, calpain-6 lacks the EF-hand calcium-binding motif and has substitutions in the canonical active site residues, making it unlikely to be proteolytically active. The gene is located on the X chromosome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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