Thermo Fisher Scientific Calpain 7 Polyclonal Antibody

Thermo Fisher Scientific Calpain 7 Polyclonal Antibody

Applications

• Western Blot (WB): 1:1,000–1:3,000

Species Reactivity

• Human
• Mouse
• Rat

Host / Isotype

• Rabbit / IgG

Class

• Polyclonal

Type

• Antibody

Immunogen

A synthesized peptide derived from human CAPN7 (Accession Q9Y6W3), corresponding to amino acid residues I298–D348.

Conjugate

• Unconjugated

Form

• Liquid

Concentration

• 1 mg/mL

Purification

• Affinity chromatography

Storage Buffer

• PBS, pH 7.4, with 50% glycerol

Contains

• 0.02% sodium azide

Storage Conditions

• −20°C

Shipping Conditions

• Wet ice

RRID

• AB_2853027

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Product Specific Information

Antibody detects endogenous levels of total CAPN7.

Target Information

Calpain proteinases are papain-like neutral proteases activated by calcium. Calpains 1 and 2 consist of a large active subunit and a small non-proteolytic enhancer subunit (calpain-4). Other calpains (5–15) generally do not require a small subunit.
Calpain-7 contains a domain-N instead of the typical EF-hand calcium-binding domain, suggesting uncertain calcium regulation. Instead of the EF-hand domain-IV, it possesses a sequence resembling domain-III with unknown function. Calpain-7 is widely distributed and found in most analyzed tissues.

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For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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