Thermo Fisher Scientific PODN Polyclonal Antibody
인간, 생쥐, 랫트 반응성의 Rabbit Polyclonal 항체로, Human PODN 합성 펩타이드에 대응합니다. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제된 고순도 제품입니다. 세포외기질 관련 연구용으로 사용됩니다.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in Human PODN |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2719508 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
Non-collagenous proteins of the small leucine-rich repeat (SLR) protein family are important components of the extracellular matrix. The extracellular matrix regulates development, tissue repair, and metastasis through cell proliferation, differentiation, adhesion, and migration.
Podocan (also known as PCAN, SLRR5A, or PODN) is a 613 amino acid secreted protein belonging to the small leucine-rich proteoglycan (SLRP) family, class V subfamily. It is expressed in kidney, heart, liver, pancreas, and vascular smooth muscle cells. Podocan exists as three alternatively spliced isoforms containing twenty LRRs, a unique N-terminal cysteine-rich cluster, and a highly acidic C-terminal domain. It is a glycoprotein with N-linked oligosaccharides that may regulate growth in cardiovascular tissues. The gene encoding Podocan is located on human chromosome 1 and interacts with type I collagen (COL1).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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