Thermo Fisher Scientific MMP28 Polyclonal Antibody
MMP28 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot에 적합합니다. 인간, 마우스, 랫트 반응성을 가지며, 항원 친화 크로마토그래피로 정제되었습니다. 피부 손상 및 신경 발달 연구에 활용 가능합니다.
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Thermo Fisher Scientific MMP28 Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in Human MMP28 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719502 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% as determined by SDS-PAGE.
Target Information
Epilysin, also known as matrix metalloproteinase-28 (MMP-28), is a secreted protein belonging to the peptidase M10A family. Matrix metalloproteinases are responsible for extracellular matrix degradation, critical for tissue remodeling, reproduction, and embryonic development.
Epilysin is produced by proliferating keratinocytes and mediates casein degradation. Its expression increases following skin injury, suggesting involvement in tissue repair and homeostasis.
Additionally, Epilysin may function in the nervous system — incubation with rat embryonic brain tissue induces myelin protein degradation. In Xenopus, Epilysin localizes to nerves and is upregulated during neurulation, indicating a conserved role in neural development and modulation of the axonal-glial extracellular environment.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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