Thermo Fisher Scientific MTCO1 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

Target Information

Cytochrome c oxidase subunit I (CO1 or MTCO1) is one of three mitochondrial DNA (mtDNA) encoded subunits (MTCO1, MTCO2, MTCO3) of respiratory Complex IV.
Complex IV is located within the mitochondrial inner membrane and is the third and final enzyme of the electron transport chain of mitochondrial oxidative phosphorylation. It consists of 13 polypeptides — subunits I, II, and III (MTCO1, MTCO2, MTCO3) are mtDNA encoded, while others are nuclear encoded.
Cytochrome c oxidase enzymes contain four redox centers: two hemes (a and a3) and two copper centers (CuA and CuB). The hemes and CuB are bound to subunit I.
Mutations in MTCO1 can affect enzyme function and mitochondrial respiratory capacity.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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