Thermo Fisher Scientific TMEM173 Monoclonal Antibody (OTI4H8), Biotin, TrueMAB
인간 TMEM173(STING) 단백질을 인식하는 Biotin 결합 단클론 항체입니다. ELISA 및 Luminex 분석에 적합하며, 고순도 친화 크로마토그래피 정제 제품입니다. PBS/BSA 완충액에 보관되며, -20°C에서 안정적으로 저장 가능합니다.
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Applications
ELISA (ELISA)
- Tested Dilution: 1:250–1:1,000
Luminex (LUM)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4H8 |
| Immunogen | Full length human recombinant protein of human TMEM173 produced in HEK293T cell |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 10 mg/mL BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
STING is a 379 amino acid signaling protein that plays a critical role in innate immune signaling. It activates NF-κB and IRF3 pathways to induce type I interferons (IFN-α and IFN-β), establishing an antiviral state. STING may also function as a translocon influencing interferon induction and mediates apoptotic signaling via MHC-II association. It is found in the endoplasmic reticulum membrane, cell membrane, and mitochondrial outer membrane, and is ubiquitously expressed across tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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