Thermo Fisher Scientific TMEM173 Monoclonal Antibody (OTI1A7), Biotin, TrueMAB
Human TMEM173(STING) 단백질을 인식하는 mouse monoclonal antibody로, Biotin으로 conjugation된 TrueMAB 포맷 제품입니다. ELISA 및 Luminex 분석에 적합하며, 고순도 affinity chromatography로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
ELISA (ELISA)
- Tested Dilution: 1:250–1:1,000
Luminex (LUM)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A7 |
| Immunogen | Full length human recombinant protein of human TMEM173 produced in HEK293T cells |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 10 mg/mL BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
STING is a 379-amino-acid signaling protein that plays a critical role in innate immune signaling. It activates NF-κB and IRF3 transcription pathways, inducing type I interferons (IFN-α and IFN-β) and promoting antiviral responses.
STING may also participate in translocon function and apoptotic signal transduction via its association with MHC-II. It facilitates detection of intracellular viral RNA and B-form DNA, and mediates death signaling through ERK pathway activation.
Typically localized to the endoplasmic reticulum membrane, cell membrane, and mitochondrial outer membrane, STING is ubiquitously expressed in most tissues.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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