Thermo Fisher Scientific CSNK1G1 Monoclonal Antibody (OTI8H1), TrueMAB
Human CSNK1G1 단백질(aa 163-422)에 특이적인 Mouse monoclonal antibody (Clone OTI8H1). Western blot에 적합하며, 1:2,000 희석 권장. Affinity chromatography로 정제된 액상 항체로, PBS/BSA/glycerol buffer에 보존. 연구용 전용 제품.
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Applications
- Western Blot (WB): Tested at 1:2,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8H1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 163–422 of human CSNK1G1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Casein kinase I (CKI) and casein kinase II (CKII) are families of serine/threonine protein kinases found in all eukaryotes. CKI family members, including CKI alpha, gamma, epsilon, and delta, are involved in regulating cytoplasmic and nuclear processes such as DNA replication and repair.
CKII typically exists as a tetrameric complex (α2β2 or αα′β2), where the alpha catalytic subunit is activated by the beta regulatory subunit, which undergoes autophosphorylation. CKII activity is high in proliferating and differentiating cells and phosphorylates over 100 substrates, including nuclear oncoproteins, transcription factors, and enzymes involved in DNA metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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