Thermo Fisher Scientific Collagen IV Monoclonal Antibody (COL-94)
인체 Collagen IV에 특이적인 단클론 항체로 다양한 면역분석(WB, IHC, ELISA 등)에 사용 가능. 고농도(4.6 mg/mL) 액상 형태로 제공되며, 인간 조직에 대한 높은 특이성을 보유. 장기 보관 시 -20°C에서 안정적으로 유지.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | View 1 publication |
| Immunohistochemistry (IHC) | - | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 | - |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent | - |
| Immunocytochemistry (ICC/IF) | Assay-dependent | View 1 publication |
| ELISA | Assay-dependent | - |
| Dot blot (DB) | Assay-dependent | - |
| Immunomicroscopy (IM) | Assay-dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Rat, Rhesus monkey |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | COL-94 |
| Immunogen | Purified full-length native human Collagen IV |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 4.6 mg/mL |
| Storage Buffer | Ascites |
| Contains | 15 mM sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_558482 |
Product Specific Information
- This antibody does not cross-react with feline, chicken, goat, rabbit, rat, or ovine species.
- Positive control: human tissue.
Target Information
Collagen IV is a key structural protein forming the basement membrane in tissues such as kidneys, lungs, and skin. It provides mechanical support and stability through its network-like structure composed of three alpha chains encoded by COL4A1, COL4A2, and COL4A3 genes. Mutations in these genes are associated with disorders like Alport syndrome and Goodpasture syndrome, affecting kidney and lung function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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