Thermo Fisher Scientific Actin-like 7A Polyclonal Antibody

Applications

• Western Blot (WB)
  Tested Dilution: 1:500–1:3,000

Product Specifications

Product Specific Information

• Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7
• Predicted reactivity: Mouse (91%), Rat (92%), Chimpanzee (98%), Bovine (92%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration, and chromatin remodeling.
The ACTL7A gene and its related gene ACTL7B are intronless and located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Although ACTL7A has been analyzed in patients with dysautonomia, it is unlikely to be involved in the pathogenesis of the disorder. The gene is expressed in a wide variety of adult tissues, but its exact function remains unknown.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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