Thermo Fisher Scientific Bcl-3 Monoclonal Antibody (Ham150-3.5)

Applications

Tested Dilution

Publications

Western Blot (WB)

2 µg/mL

-

Flow Cytometry (Flow)

1 µg/test

-

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Armenian hamster / IgG

Class

Monoclonal

Type

Antibody

Clone

Ham150-3.5

Immunogen

Full length mouse Bcl-3 protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:BCL-3,uniProtId:Q9Z2F6-1,ncbiNodeId:10090,antigenRange:1-448,antigenLength:448,antigenImageFileName:MA1-950_BCL-3_Q9Z2F6-1_Armenian_hamster.svg,antigenImageFileNamePDP:MA1-950_BCL-3_Q9Z2F6-1_Armenian_hamster_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

PBS with 1mg/mL BSA

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_325094

Product Specific Information

MA1-950 detects human and mouse Bcl-3 from transfected cells and shows no cross-reactivity to other Bcl isoforms.

MA1-950 has been successfully used in Western blot and FACS procedures. By Western blot, this antibody detects an ~47 kDa protein representing Bcl-3 from C57BI/6 human T cells and Bcl-3 transgenic ms T cells.

MA1-950 immunogen is full length Bcl-3 protein from mouse.

Target Information

B cell Lymphoma 3 is a member of the IkB subfamily of inhibitors. This subfamily is part of the NF-kB transcription factor protein family and it is suggested that a balance in the concentration of various NF-kB family members regulates apoptosis and survival of activated T cells. Bcl-3 has been shown to have versatile functions such as cytoplasmic activation of p50 homodimers, translocation to the nucleus, and modulation of the transcriptional machinery in the nucleus. Bcl-3 activity often relies on several nuclear interacting proteins such as Tip60, Jab1, Bard1, and Pirin.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.