Thermo Fisher Scientific Bcl-3 Monoclonal Antibody (Ham150-3.5)
인간 및 생쥐 Bcl-3 단백질을 검출하는 단클론 항체로 Western blot, Flow cytometry, ELISA에 적합함. Armenian hamster 유래 IgG이며 Protein G로 정제된 액상 형태. PBS/BSA 버퍼에 보관하며 -20°C에서 안정적 저장 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2 µg/mL |
| Flow Cytometry (Flow) | 1 µg/test |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Armenian hamster / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | Ham150-3.5 |
| Immunogen | Full length mouse Bcl-3 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_325094 |
Product Specific Information
MA1-950 detects human and mouse Bcl-3 from transfected cells and shows no cross-reactivity to other Bcl isoforms.
It has been successfully used in Western blot and FACS procedures.
By Western blot, this antibody detects an ~47 kDa protein representing Bcl-3 from C57BI/6 human T cells and Bcl-3 transgenic mouse T cells.
The immunogen is full-length Bcl-3 protein from mouse.
Target Information
B cell Lymphoma 3 (Bcl-3) is a member of the IkB subfamily of inhibitors, which is part of the NF-kB transcription factor family.
A balance in the concentration of various NF-kB family members regulates apoptosis and survival of activated T cells.
Bcl-3 functions in cytoplasmic activation of p50 homodimers, nuclear translocation, and modulation of transcriptional machinery.
Its activity involves nuclear interacting proteins such as Tip60, Jab1, Bard1, and Pirin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: MA1-950_BCL-3_Q9Z2F6-1_Armenian_hamster.svg, MA1-950_BCL-3_Q9Z2F6-1_Armenian_hamster_PDP.jpeg)
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