Thermo Fisher Scientific CD80 Recombinant Rabbit Monoclonal Antibody (3C3)
CD80 단백질을 인식하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체(3C3). Western blot, IHC, IP 등 다양한 응용 가능. 고순도 액상 형태로 제공되며, 인간 시료 반응성. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunoprecipitation (IP) | 1:200–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 3C3 |
| Immunogen | A synthesized peptide derived from human CD80 (B7-1), UniProt ID: P33681-1, antigen range: 277–288 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 150 mM NaCl |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2898242 |
Product Specific Information
This antibody has been tested in direct-ELISA.
Target Information
CD80 (B7-1) and CD86 (B7-2) are ligands of the T cell costimulatory molecule CD28 and the inhibitory receptor CTLA-4 (CD152). Both are expressed on professional antigen-presenting cells and are essential for T cell activation. CD80 is rapidly induced on activated B cells, EBV-transformed B cell lines, Burkitt’s lymphoma cell lines, follicular B lymphoma cells, T cells, and monocytes. CD80 dysfunction is associated with diseases such as gallbladder squamous cell carcinoma and myocarditis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: MA5-38327_CD80_B7-1_P33681-1_Rabbit.svg)
(이미지 파일명: MA5-38327_CD80_B7-1_P33681-1_Rabbit_PDP.jpeg)
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