Thermo Fisher Scientific RIMS1/RIM1 Polyclonal Antibody
RIMS1/RIM1 단백질을 인식하는 Rabbit Polyclonal Antibody로 신경전달 및 시냅스 소포 분비 연구에 적합. Western blot 및 Immunoprecipitation에 사용 가능. 1 mg/mL 농도의 액상 형태로 제공되며 4°C에서 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 975 to 1025 of Human Regulating synaptic membrane exocytosis protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Rat
Target Information
RIMS1 is a member of the RAS gene superfamily that regulates synaptic vesicle exocytosis. It plays a role in the regulation of voltage-gated calcium channels during neurotransmitter and insulin release. Mutations in the RIMS1 gene are associated with cone-rod dystrophy type 7 and retinitis pigmentosa. RIMS1 may function as a scaffold protein regulating neurotransmitter release at the active zone and is essential for maintaining normal release probability and short-term synaptic plasticity. It also contributes to dendrite formation by melanocytes. Multiple transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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