Thermo Fisher Scientific CD131 Monoclonal Antibody (1C1), Biotin, eBioscience
인간 CD131(Common β Subunit)을 인식하는 Mouse IgG1 단클론 항체로, Biotin으로 표지되어 있습니다. Flow Cytometry에 최적화되어 있으며 0.5 µg/test로 검증되었습니다. IL-3, IL-5, GM-CSF 수용체 분석 및 염증 반응 연구에 적합합니다.
- 카탈로그번호
- 13-1319-82
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- pk
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Applications
Tested Application
- Flow Cytometry (Flow)
Tested Dilution
- 0.5 µg/test
Publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG1, kappa |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), Biotin, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1C1 |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2572777 |
| Filtration | 0.2 µm post-manufacturing filtered |
Additional Formats
Product Specific Information
The 1C1 monoclonal antibody reacts with human CD131, also known as the common beta subunit (βC).
This subunit associates with alpha subunits of IL-3, IL-5, and GM-CSF receptors to form high-affinity cytokine receptors.
These receptors are expressed on neutrophils, eosinophils, monocytes, endothelial cells, fibroblasts, and hematopoietic progenitor cells, playing a crucial role in eosinophil activation and inflammatory response.
Applications Reported: Suitable for flow cytometric analysis.
Applications Tested: Tested on normal human peripheral blood cells at ≤ 0.5 µg/test (100 µL final volume).
Cell number may range from 10⁵ to 10⁸ cells/test and should be optimized per assay.
Target Information
The encoded protein is the common beta chain of the high-affinity receptor for IL-3, IL-5, and CSF.
Defects in this gene are associated with pulmonary alveolar proteinosis (PAP).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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