Thermo Fisher Scientific IDH3G Polyclonal Antibody
Thermo Fisher Scientific의 IDH3G Polyclonal Antibody는 인간, 마우스, 랫트에 반응하는 Rabbit IgG 형 항체로, WB, IHC, ICC/IF에 사용 가능합니다. 항원 친화 크로마토그래피로 정제되었으며 PBS 버퍼에 보관됩니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific IDH3G Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human IDH3G. Recombinant protein control fragment (Product #RP-92111). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642625 |
Product Specific Information
Immunogen sequence:
ADEEDIRNAI MAIRRNRVAL KGNIETNHNL PPSHKSRNNI LRTSLDLYAN VIHCKSLPGV VTRHKDIDIL IVRENTEGEY SSLEHESVAG VVESLKIITK AKSLRIAEYA FKLAQESGRK KVTAVHKANI MKLGDGLFLQ CCREVAA
Highest antigen sequence identity to orthologs:
- Mouse: 100%
- Rat: 100%
Target Information
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one utilizing NAD(+) and the other NADP(+) as electron acceptors.
Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent enzymes localized to the mitochondrial matrix and two NADP(+)-dependent enzymes (one mitochondrial, one cytosolic).
NAD(+)-dependent isocitrate dehydrogenases catalyze the rate-limiting step of the tricarboxylic acid cycle. Each isozyme consists of two alpha subunits, one beta subunit, and one gamma subunit.
The IDH3G gene encodes the gamma subunit of one NAD(+)-dependent isozyme and is a candidate gene for periventricular heterotopia. Several alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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