Thermo Fisher Scientific ALK Monoclonal Antibody (OTI6G8), TrueMAB
인간 ALK 단백질(AA 1060-1620)에 특이적인 Mouse IgG1 단클론 항체. Western blot에 최적화된 TrueMAB 형식. 액상 형태로 1 mg/mL 농도, PBS/BSA/glycerol 완충액에 보관. 뇌 발달 및 종양 관련 ALK 연구에 적합.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6G8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1060–1620 of human ALK produced in SF9 cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Anaplastic Lymphoma Receptor Tyrosine Kinase (ALK) belongs to the insulin receptor superfamily and is vital for brain development. Mutations, rearrangements, and amplifications in the ALK gene are associated with tumors such as anaplastic large cell lymphoma, neuroblastoma, and non-small cell lung cancer. Chromosomal rearrangements commonly lead to fusion genes like NPM-ALK, which are oncogenic. ALK encodes a receptor protein-tyrosine kinase with transmembrane and extracellular domains, showing high similarity to LTK. It plays an important role in neuronal development and function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송 정보
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