Thermo Fisher Scientific WASL Monoclonal Antibody (OTI1A10), TrueMAB
인간 WASL 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western Blot에 1:2,000 희석으로 검증됨. 액상 형태이며, PBS/BSA/glycerol buffer에 보관. 세포 골격 신호전달 연구용으로 적합.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A10 |
| Immunogen | Full-length human recombinant WASL protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structures and are involved in transduction of signals from cell surface receptors to the actin cytoskeleton.
These proteins interact with multiple partners, including the small GTPase Cdc42 and the Arp2/3 complex, which regulate actin filament formation.
WASL (N-WASP) is a homolog of WAS protein, ubiquitously expressed with highest levels in neural tissues. It binds Cdc42 directly and induces formation of long actin microspikes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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