Thermo Fisher Scientific NAGA Monoclonal Antibody (OTI8H7), TrueMAB
인간 NAGA 단백질을 인식하는 Mouse IgG1 단일클론 항체. Western blot에 최적화되어 있으며, 고순도 친화 크로마토그래피로 정제됨. PBS/BSA/glycerol buffer에 보관, 연구용으로만 사용.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8H7 |
| Immunogen | Full length human recombinant NAGA protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
NAGA (N-acetylgalactosaminidase, alpha), also known as alpha-galactosidase B or GALB, is a 411 amino acid lysosomal protein belonging to the glycosyl hydrolase 27 family. It may exist as a homodimer and plays a critical role in glycolipid breakdown.
NAGA encodes alpha-N-acetylgalactosaminidase, a lysosomal enzyme that cleaves alpha-N-acetylgalactosaminyl groups from glycoconjugates.
It maps to human chromosome 22q13.2, and defects in NAGA cause Schindler disease (types I, II, III), also known as NAGA deficiency.
Schindler disease type I is the most severe, type III has mild to moderate effects, and type II (Kanzaki disease) is characterized by mild intellectual impairment and angiokeratoma corporis diffusum.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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